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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC27
All Species:
28.18
Human Site:
S721
Identified Species:
51.67
UniProt:
P30260
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30260
NP_001107563.1
824
91867
S721
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
Chimpanzee
Pan troglodytes
XP_511624
824
91839
S721
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
Rhesus Macaque
Macaca mulatta
XP_001115994
824
91959
S721
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
Dog
Lupus familis
XP_548047
825
91842
S722
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_663411
825
91824
S722
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
Rat
Rattus norvegicus
NP_001019964
824
91645
S721
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520967
385
43892
A291
H
I
G
V
V
Q
H
A
L
K
K
S
E
K
A
Chicken
Gallus gallus
NP_001006331
833
92606
S722
F
A
N
E
K
Y
K
S
A
L
Q
E
L
E
E
Frog
Xenopus laevis
NP_001085568
833
92363
L722
F
A
N
E
K
Y
K
L
A
L
Q
E
L
E
E
Zebra Danio
Brachydanio rerio
NP_958857
790
87878
P696
E
E
L
K
Q
I
V
P
K
E
S
L
V
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648093
900
101266
E799
F
S
L
G
K
Y
Q
E
A
L
R
E
L
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786824
824
91473
D708
F
A
T
E
K
Y
Q
D
A
L
K
E
L
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38042
758
85418
Y664
Y
K
E
K
A
L
Q
Y
Y
E
L
A
C
H
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
96.3
99.1
N.A.
96.9
97.4
N.A.
43.6
94.5
89.6
76.5
N.A.
39.2
N.A.
N.A.
49.2
Protein Similarity:
100
99.8
97.2
99.2
N.A.
98.6
98.5
N.A.
45.2
96.6
94.5
84.3
N.A.
57.4
N.A.
N.A.
67.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
93.3
0
N.A.
60
N.A.
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
93.3
20
N.A.
80
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
0
0
8
0
0
8
77
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
8
8
8
70
0
0
0
8
0
16
0
77
8
77
77
% E
% Phe:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
16
77
0
62
0
8
8
16
0
0
8
0
% K
% Leu:
0
0
16
0
0
8
0
8
8
77
8
8
77
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
8
24
0
0
0
62
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
54
0
0
8
8
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
77
0
8
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _